The institutional capacity of the Health Sector and the response to COVID-19 in a global perspective. / A capacidade institucional do Setor Saúde e a resposta à COVID-19 em perspectiva global.

This study approaches the Global Health Security Index (GHSI) according to the responses to the first cycle of the COVID-19. The GHSI ranks countries' institutional capacity to address biological risks. We analyzed data regarding the spread of COVID-19 pandemic in 50 countries to assess the ability of GHSI to anticipate health risks. The lack of vaccination determined the spread of the COVID-19 in the first cycle of the pandemic in 2020. Country indicators are correlated and demonstrated by descriptive statistics. The clustering method groups countries by similar age composition. The main restriction that can be attributed to the GHSI concerns the preference of biomedical variables for measuring institutional capacity. Our work shows that the pandemic had a significant impact on better-prepared countries, according to the GHSI, to control the spread of diseases and offer more access to health care in 2020. This paper points out that the health sector depended on the cooperation of governments in the adoption of social distancing during the first cycle of the pandemic. The GHSI failed to consider the role of political leaders who challenge severe health risks by vetoing social distancing.

O artigo analisa o Índice da Segurança Sanitária Global (ISSG) à luz das respostas nacionais ao primeiro ciclo da pandemia da COVID-19. O ISSG classifica a capacidade dos países no enfrentamento dos riscos biológicos graves. O artigo examina os dados da pandemia de 50 países para avaliar o poder preditivo do ISSG. A ausência da vacinação determinou difusão da COVID-19 no primeiro ciclo da pandemia em 2020. Os indicadores dos países são correlacionados e demonstrados por estatística descritiva. A metodologia de aglomeração por clusters agrupa os países segundo a similaridade da composição etária. A principal restrição que pode ser atribuída ao ISSG diz respeito ao privilegiamento das variáveis biomédicas para a mensuração da capacidade institucional. O artigo evidencia que, paradoxalmente, o primeiro ciclo da pandemia teve um impacto significativo nos países teoricamente mais preparados, segundo o ISSG, para controlar a disseminação de doenças e oferecer mais acesso à assistência à saúde. O artigo assinala que durante o primeiro ciclo da pandemia, o setor saúde dependeu da cooperação dos governos na adoção do distanciamento social. O ISSG não considerou o papel das lideranças políticas que desafiam o risco sanitário severo por veto às medidas de distanciamento social.

Viral Coinfection of Children Hospitalized with Severe Acute Respiratory Infections during COVID-19 Pandemic.

The main pathogens of severe respiratory infection in children are respiratory viruses, and the current molecular technology allows for a rapid and simultaneous detection of a wide spectrum of these viral pathogens, facilitating the diagnosis and evaluation of viral coinfection. METHODS: This study was conducted between March 2020 and December 2021. All children admitted to the ICU with a diagnosis of SARI and who were tested by polymerase chain reaction on nasopharyngeal swabs for SARS-CoV-2 and other common respiratory viral pathogens were included in the study. RESULTS: The result of the viral panel identified 446 children, with one infected with a single virus and 160 co-infected with two or more viruses. This study employed descriptive analyses, where a total of twenty-two coinfections among SARI-causing viruses were identified. Thus, the five most frequent coinfections that were selected for the study are: hRV/SARS-CoV-2 (17.91%), hRV/RSV (14.18%), RSV/SARS-CoV-2 (12.69%), hRV/BoV (10.45%), and hRV/AdV (8.21%). The most significant age group was 38.1%, representing patients aged between 24 and 59 months (61 individuals). Patients older than 59 months represented a total of 27.5%, comprising forty-four patients. The use of oxygen therapy was statistically significant in coinfections with Bocavirus, other CoVs, Metapneumovirus, and RSV. Coinfections with SARS-CoV-2 and the other different coinfections presented a similar time of use of oxygen therapy with a value of (p > 0.05). In the year 2020, hRV/BoV was more frequent in relation to other types of coinfections, representing a total of 35.1%. The year 2021 presented a divergent profile, with hRV/SARS-CoV-2 coinfection being the most frequent (30.8%), followed by hRV/RSV (28.2%). Additionally, 25.6% and 15.4% represented coinfections between RSV/SARS-CoV-2 and hRV/AdV, respectively. We saw that two of the patients coinfected with hRV/SARS-CoV-2 died, representing 9.52% of all deaths in the study. In addition, both hRV/hBoV and hRV/RSV had death records for each case, representing 8.33% and 6.67% of all deaths, respectively. CONCLUSION: Coinfections with respiratory viruses, such as RSV and hBoV, can increase the severity of the disease in children with SARI who are admitted to the ICU, and children infected with SARS-CoV-2 have their clinical condition worsened when they have comorbidities.

Study of ozone misting for sanitization of hospital facilities: A CFD approach

The COVID-19 pandemic has demonstrated the demand for more effective procedures for sanitizing environments, especially high-risk ones, such as hospitals. Several products are used as disinfectants, with ozone being one of the strongest oxidants known. High relative humidity helps reduce the contact time required for viruses and bacteria inactivation with ozone. Thus, this work aimed to analyze the dispersion of an ozonized mist by CFD simulation to sanitize a hospital operating room. To our best knowledge, for the first time, the dispersion of an ozonized mist was investigated by CFD. The mathematical and numerical models were validated with results from the literature. The decay kinetics of the ozonized mist was obtained experimentally, resulting in a first order reaction with a kinetic constant of 2.66 × 10−4 s−1. The numerical results of concentration on the surfaces were analyzed qualitatively and quantitatively, providing relevant information about the fluid dynamics of the sanitizing process. Ozone mist concentrations were higher on the walls close to the generator and lower on the furthest walls and the ceiling. The ozone mist concentration in the room reached an average of 11 mg/L. Five minutes of ozone mist generation and another five minutes of decay by air circulation were sufficient to provide an increase in ozone mist to concentrations above 4 mg/L, considered satisfactory for the sanitization of the operating room surfaces. [ FROM AUTHOR] Copyright of Ozone: Science & Engineering is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)

Profile analysis of emerging respiratory virus in children.

Acute respiratory infections (ARIs) are caused by a variety of microorganisms. Of all ARIs, 80% are caused by viruses such as human respiratory syncytial virus, metapneumovirus, influenza, parainfluenza, rhinovirus, and, more recently, Sars-CoV-2, which has been responsible for the COVID-19 pandemic. The objective of our study was to evaluate clinical data from a viral panel performed in children hospitalized with SARS or COVID-19 in the infirmary or ICU of 5 pediatric hospitals in the city of Goiânia, Goiás, Brazil. Demographic, clinical, and laboratory data were collected for analysis, and data on the outcomes underwent statistical treatment. A total of 128 patients were selected for the study, 54% of whom were male and 46% female. The viral panel included rhinovirus, COVID-19, metapneumovirus, adenovirus, and parainfluenza. Descriptive analyses of age profile showed differences in the involvement of particular viruses. The percentage of patients who required hospitalization in the ICU, infirmary, as well as individuals who were discharged after therapy or who died, were described. Our work shows that epidemiological surveillance measures are indispensable, especially if used in the continued analysis of viral panels in all pediatric patients with SARS.

Impaired Neuromuscular Efficiency and Symptom-Limited Aerobic Exercise Capacity 4 Weeks After Recovery From COVID-19 Appear to Be Associated With Disease Severity at Onset.

OBJECTIVE: The objectives of this study were to evaluate neuromuscular recruitment and efficiency in participants who recovered from COVID-19 and assess the association between neuromuscular efficiency and symptom-limited aerobic exercise capacity. METHODS: Participants who recovered from mild (n = 31) and severe (n = 17) COVID-19 were evaluated and compared with a reference group (n = 15). Participants underwent symptom-limited ergometer exercise testing with simultaneous electromyography evaluation after a 4-week recovery period. Activation of muscle fiber types IIa and IIb and neuromuscular efficiency (watts/percentage of root-mean-square obtained at the maximum effort) were determined from electromyography of the right vastus lateralis. RESULTS: Participants who had recovered from severe COVID-19 had lower power output and higher neuromuscular activity than the reference group and those who had recovered from mild COVID-19. Type IIa and IIb fibers were activated at a lower power output in participants who had recovered from severe COVID-19 than in the reference group and those who had recovered from mild COVID-19, with large effect sizes (0.40 for type IIa and 0.48 for type IIb). Neuromuscular efficiency was lower in participants who had recovered from severe COVID-19 than in the reference group and those who had recovered from mild COVID-19, with a large effect size (0.45). Neuromuscular efficiency showed a correlation with symptom-limited aerobic exercise capacity (r = 0.83). No differences were observed between participants who had recovered from mild COVID-19 and the reference group for any variables. CONCLUSION: This physiological observational study supports the notion that more severe COVID-19 symptoms at disease onset appear to correspondingly impair neuromuscular efficiency in survivors over a short time frame of 4 weeks after recovery, potentially contributing to reduced cardiorespiratory capacity. Further studies are needed to replicate and extend these findings with respect to their clinical implications for assessment/evaluation and interventions. IMPACT: After 4 weeks of recovery, neuromuscular impairment is particularly evident in severe cases; this problem may contribute to reduced cardiopulmonary exercise capacity.

Psychometric properties of the Brazilian version of the fear of COVID-19 scale (FCV-19S).

COVID-19 can bring several psychological problems to patients and non-patients, which highlights the need for a better understanding of outcomes that can emerge due the occurrence of the virus. One of these variables is fear, present in situations of continuous uncertainty. Fear is a key variable for mental health and tracking it and its correlates might help to develop proper education and prevention programs. Currently, Brazil is one of the epicentres of the COVID-19 pandemic, with its public health system scrapped and not being able to contain the amount of infected people. Therefore, a proper measure to screen the fear of COVID-19 will help to provide improvements in mental health in such contexts. For that, two studies were performed. In Study 1 (N = 230) we assessed the factorial structure of the measure through exploratory factor analysis, and item parameters using item response theory. In Study 2 (N = 302), we assessed whether the structure would replicate in an independent sample and through confirmatory factor analysis, besides assessing convergent validity using Structural Equation Modelling and proposing a shorter version of the measure. Both long and short versions presented a reliable unidimensional structure and similar patterns of correlations with depression, anxiety, and stress. Overall, our results showed that the FCV-19S and its short version are useful measures to the assessment of fear of COVID-19 in Brazil.

Women and working in healthcare during the Covid-19 pandemic in Brazil: bullying of colleagues.

BACKGROUND: Based on a feminist approach, we analyzed the experiences of workplace bullying suffered by women front-line healthcare professionals dealing with the Covid-19 pandemic. We start from studies that show that women make up 70% of the global health workforce, 85% in the area of nursing, and 90% in the case of social care workers. An unequivocal need thus exists to address gender issues regarding the composition of the labor force in the health area. The pandemic has aggravated recurring problems involving healthcare professionals at the various caregiving levels, such as mental harassment (bullying) and its effects on mental health. METHODS: Data were gathered from an online survey of a convenience (non-probability) sample composed of 1,430 volunteer respondents, all women that work in the public health system in Brazil. The analyses and discussions involved the responses to a questionnaire containing 12 closed-ended questions and one open-ended question. RESULTS: The results revealed a context of workplace bullying aggravated by precarious material, institutional and organizational conditions in the area of health services against the backdrop of the Covid-19 pandemic in Brazil. This context has variously led to aggression, isolation, heavy workloads, and invasion of privacy, humiliation, persecution and fear as it was possible to see, mainly, in the answers to the study's open-ended question. This situation degrades both work relations and the integrity of the healthcare professionals who work on the front line to treat Covid-19 cases. CONCLUSION: We conclude that bullying is a psychosocial phenomenon that heightens the oppression and subordination still experienced by women in the contemporary context, but with new hues in a scenario of frontline response to Covid-19.

Characterization of T Helper 1 and 2 Cytokine Profiles in Newborns of Mothers with COVID-19.

An infectious disease caused by SARS-CoV-2, COVID-19 greatly affects the pediatric population and is 3 times more prevalent in newborns than in the general population. In newborns, the overexpression of immunological molecules may also induce a so-called cytokine storm. In our study, we evaluated the expression of cytokines in newborns admitted to a neonatal ICU whose mothers had SARS-CoV-2 and symptoms of SARS. The blood of newborns of infected and healthy mothers was collected to identify their Th1 and Th2 cytokine profiles, and via flow cytometry, the cytokines TNF-α, IFN-γ, IL-2, IL-6, and IL-10 were identified. Overexpression was observed in the Th1 and Th2 cytokine profiles of newborns from infected mothers compared with the control group. Statistical analysis also revealed significant differences between the cellular and humoral responses of the infected group versus the control group. The cellular versus humoral responses of the newborns of infected mothers were also compared, which revealed the prevalence of the cellular immune response. These data demonstrate that some cytokines identified relate to more severe symptoms and even some comorbidities. IL-6, TNF-α, and IL-10 may especially be related to cytokine storms in neonates of mothers with COVID-19.

Bibliometric Analysis of the Scientific Production on Compassion Fatigue.

BACKGROUND: Compassion fatigue is a common phenomenon among healthcare professionals and includes several concepts that share a direct relationship with quality of life, with consequences on both physical and emotional well-being but also at the economic and organizational levels. OBJECTIVES: To analyze the profile of scientific publications on compassion fatigue, dissecting trends, and highlighting research opportunities. METHOD: Bibliometric analysis based on Donthu's guidelines, data collection from Web of Science (Clarivate Analytics), and analytic techniques (performance analysis and science mapping) with VOSviewer® and CiteSpace®. RESULTS: We obtained 1364 articles and found that the concept emerged in 1995 and is frequently associated with areas of general health. Through analysis, we identified the following research frontiers: "vicarious traumatization", "working", "survivor", "mental health", and "impact". CONCLUSION: There has been a growing interest in this subject among researchers, with an increase in scientific production related to areas of health such as nursing, providing a solid starting point for further investigation. Registration number from the Open Science Framework: osf.io/b3du8.

Factors associated with death due to severe acute respiratory syndrome caused by influenza: Brazilian population study

Introduction Influenza infection is characterized by acute viral infection of high transmissibility. Worsening of the case can lead to the need for hospitalization, severe acute respiratory syndrome (SARS) and even death. Method This is a cross-sectional population-based study that used secondary database from the Brazilian Influenza Epidemiological Surveillance Information System. Only cases of adults with diagnosis of influenza by RT-PCR and case evolution recorded were included. Results We identified 2,273 adults with SARS by influenza, 343 of which had death as an outcome. The main risk factors for death were lack of hospitalization, not having cough and age, both with p<0.001. In addition, without asthma, having black skin color, not receiving flu vaccine, having brown skin color and not having a sore throat (p≤ 0.005) were risk factors too. Conclusion Factors associated with death due to SARS caused by influenza in Brazil, risk factors and protective factors to death were identified. It was evident that those who did not receive the flu vaccine presented twice the risk of unfavorable outcome, reinforcing the need to stimulate adherence to vaccination adhering and propose changes in public policies to make influenza vaccines available to the entire population, in order to prevent severe cases and unfavorable outcomes.

Severe Neurological Manifestation in a Child with Multisystem Inflammatory Syndrome.

BACKGROUND AND OBJECTIVES: During the COVID-19 pandemic, we followed with concern the evolution of several children diagnosed with Multisystem Inflammatory Syndrome in Children (MIS-C). The purpose of this study is to describe the evolution of MIS-C in a previously healthy 3-year-old girl. METHODS: We tracked the daily medical report of all children admitted with suspected MIS-C to the five largest regional hospitals. RESULTS: Our screening identified a child who had several neurological complications associated with MIS-C. We report hematological alterations, transient cardiac dysfunction, and cerebral involvements such as laminar cortical necrosis caused by ischemic stroke. We present the course of treatment and clinical outcome, and other complications such as a severe subglottic stenosis occurring after extubation. CONCLUSION: Subglottic stenosis is an expected complication after prolonged intubation, and the presence of dysphonia and/or stridor is an important predictive factor. MIS-C with severe neurological alteration may occur in a healthy child, and early diagnosis and treatment with a pulse of corticoid with immunoglobulin are essential for a favorable outcome.

Influenza and other respiratory viruses in children: prevalence and clinical features.

With the COVID-19 pandemic still ongoing, the annual season of influenza and other respiratory virus epidemics has arrived. Specimens from patients suspected of respiratory viruses infection were collected. Viral detection was performed following RNA extraction and real-time RT-PCR. During the study period, we received and tested a total of 606 specimens. Rhinovirus virus was the viral type most prevalent, detected in 186 (45.47%) specimens. The age range of patients positive for influenza A, influenza A (H1N1), and influenza B was 18 days to 13 years. With female prevalence for this viral type, cough and asthma were the main clinical manifestations presented by this viral type. Our results indicate that rhinoviruses, adenoviruses, metapneumoviruses, and influenza are among the most important agents of ARI in pediatrics. The epidemic period of respiratory infections observed in Goiânia can be useful for planning and implementing some prevention strategies.

INQUÉRITO SOROLÓGICO PARA SARS-COV-2 E DETECÇÃO VIRAL EM CRIANÇAS E ADOLESCENTES SUBMETIDOS AO TRANSPLANTE RENAL

Introdução Com o surgimento da pandemia causada pelo SARS-CoV-2, tornou-se urgente entender a fisiopatologia e interação deste, com outros patógenos em diferentes situações clínicas, especialmente naquelas em que o paciente se encontra em maior risco e vulnerabilidade, como é o caso dos portadores de doença renal crônica submetidos ao transplante renal. Objetivo Verificar a soroprevalência de SARS-CoV-2 em crianças e adolescentes transplantados renais e um acompanhante (pai, mãe ou responsável). Método Trata-se de um estudo transversal desenvolvido no Ambulatório de Transplante Renal Pediátrico, do Hospital do Rim e Hipertensão (Fundação Oswaldo Ramos). Adotou-se como critérios de inclusão: idade ≤ a 18 anos, aceitar participar do estudo com assinatura do TALE/TCLE, realizar coleta de exames laboratoriais no laboratório do Hrim. Resultados Foram incluídos 18 crianças e adolescentes transplantados renais, com idade média 12,38 anos, mínima 4 e máxima 18 anos de idade. 11 (61,1%) participantes do sexo masculino. Em relação ao teste sorológico, 4 (22,2%) não haviam se vacinado contra COVID-19 no momento do teste. Destes, 2 (50%) apresentaram sorologia não reagente e 2 (50%) Reagente. Dentre os que receberam pelo menos 1 dose da vacina (14), 3 (21,4%) apresentaram resultado não reagente e 11 (78,6%) Reagente. Entre os 18 acompanhantes, a média de idade foi de 35 anos, 16 (88,88%) do sexo feminino. Para o teste sorológico, considerou-se 17 acompanhantes, visto que 1 não apresentou informações sobre a vacinação. 1 (5,88%) não recebeu vacina contra COVID-19 e apresentou teste sorológico Reagente. Dentre os 16 vacinados, todos estavam com sorologia Reagente para o SARS-CoV-2. Conclusão Os resultados demonstram a importância de conhecer o status sorológico de pacientes e acompanhantes, mesmo que vacinados, a fim de proporcionar maior segurança em saúde para todos os envolvidos no tratamento e acompanhamento ambulatorial do paciente transplantado. Além disso, estes achados poderão propor e mudar protocolos assistenciais, de prevenção e controle de infecção, estabelecer escore de risco, visto que se trata de uma população de maior risco e gravidade. Vale destacar o impacto social que medidas de prevenção e controle de infecção baratas, de fácil e imediata implantação no SUS, podem trazer à qualidade de vida, qualidade do cuidado, sobrevida do paciente e do enxerto, e para a segurança em saúde. Ag. Financiadora FAPESP;CAPES. Nr. Processo 2021/04492-1.

ORAL LESIONS ON A COVID-19 PATIENT: AN AUTOPSY STUDY TO ELUCIDATE COINFECTION

We present a case of a patient who died of complications of COVID-19. A 29-year-old woman presented multiple bleeding ulcerous lesions involving lips and inner lip mucosa. The patient was pregnant (29th week) and presented fever, diarrhea, dyspnea, nausea, dysgeusia, and anosmia in a 27-day evolution until death. The patient was admitted to the intensive care unit, submitted to mechanical ventilation and extracorporeal membrane oxygenation, developed fetal distress, and was submitted to an emergency C-section. Cause of death was a cardiogenic shock. During minimally invasive autopsy, oral lesions were identified and postmortem biopsy was performed. Clinical hypotheses were SARS-CoV-2 vs herpes virus. The histopathologic analyses revealed mononuclear inflammatory infiltrate, and keratinocytes showed no viral inclusion or cytopathic alterations. A large amount of a cuboid shaped gram-positive coccus in a tetrad packet arrangement was observed, compatible with Sarcina ventriculi. An abundant amount of Candida spp. was also observed. Samples were negative for immunohistochemistry to anti-SARS-CoV-2, herpes simplex virus, and cytomegalovirus.

Study of ozone misting for sanitization of hospital facilities: A CFD approach

The COVID-19 pandemic has demonstrated the demand for more effective procedures for sanitizing environments, especially high-risk ones, such as hospitals. Several products are used as disinfectants, with ozone being one of the strongest oxidants known. High relative humidity helps reduce the contact time required for viruses and bacteria inactivation with ozone. Thus, this work aimed to analyze the dispersion of an ozonized mist by CFD simulation to sanitize a hospital operating room. To our best knowledge, for the first time, the dispersion of an ozonized mist was investigated by CFD. The mathematical and numerical models were validated with results from the literature. The decay kinetics of the ozonized mist was obtained experimentally, resulting in a first order reaction with a kinetic constant of 2.66 × 10−4 s−1. The numerical results of concentration on the surfaces were analyzed qualitatively and quantitatively, providing relevant information about the fluid dynamics of the sanitizing process. Ozone mist concentrations were higher on the walls close to the generator and lower on the furthest walls and the ceiling. The ozone mist concentration in the room reached an average of 11 mg/L. Five minutes of ozone mist generation and another five minutes of decay by air circulation were sufficient to provide an increase in ozone mist to concentrations above 4 mg/L, considered satisfactory for the sanitization of the operating room surfaces. [ FROM AUTHOR] Copyright of Ozone: Science & Engineering is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)

SARS-CoV-2 in saliva, viremia and seroprevalence for COVID-19 surveillance at a single hematopoietic stem cell transplantation center: a prospective cohort study.

This prospective cohort study aims to analyze the surveillance of COVID-19 at a single hematopoietic stem cell transplantation (HSCT) center in Brazil, in 29 patients undergoing allogeneic HSCT and 57 healthcare workers (nurses and dentists), through viral shedding of SARS-CoV-2 in saliva and plasma and seroprevalence of anti-SARS-CoV-2 IgG. In addition, we report two cases with prolonged persistent detection of SARS-CoV-2 without seroconversion. The sample collection was performed seven times for patients and five times for healthcare workers. Only two patients tested positive for SARS-CoV-2 in their saliva and plasma samples (6.9%) without seroconversion. All healthcare workers were asymptomatic and none tested positive. Two patients (6.9%) and four nurses (8%) had positive serology. No dentists had positive viral detection or positive serology. Our results reflect a low prevalence of positive RT-PCR and seroprevalence of SARS-CoV-2 in patients and healthcare workers at a single HSCT center. Results have also corroborated how the rigorous protocols adopted in transplant centers were even more strengthened in this pandemic scenario.

Fake news and the seven sins of capital: a metaphorical analysis of vices in the context of the COVID-19 pandemic. / As fake news e os sete pecados do capital: uma análise metafórica de vícios no contexto pandêmico da COVID-19.

Health crises spawn "sins" and moral deformities in society that are evident when they emerge but had seemed to be dormant to collective awareness before. Through the metaphor of the seven capital sins, the article analyzes the phenomenon of fake news in the social media and in the scenario of the COVID-19 pandemic: the lust of sensationalism through the seduction and exploitation of vulnerabilities associated with fear of death; gluttony for confirmatory contents that spread untruths in the attempt to turn versions into facts; the catechism of denialism, fueling wrath or hate in restrictive epistemic environments; the greed of new technologies in the attention economy through engagement as a new commodity; competition for the spotlights of media visibility and derived gains that incite pride and envy in researchers that confuse public meaning with fake research, in a cycle that feeds sensationalism, gluttony, hate, and greed in attention capitalism. Finally, sloth is portrayed as the capital sin of opting for communicative inaction. In the comfort of bubbles, people renounce dialogue out of aversion to dissent, settling for positions of epistemic comfort. In short, the fake news phenomenon in the COVID-19 pandemic is portrayed here as the convergence of various vices that materialize as misinformation, in the communicative vacuity of the moments in which we are obliged to address each other to share our worldviews.

As crises sanitárias fazem surgir "pecados" e deformidades morais da sociedade que, embora evidentes quando despontam, pareciam antes dormentes à percepção coletiva. Por meio da metáfora dos sete pecados capitais, o texto analisa o fenômeno das fake news nas mídias sociais e no cenário da pandemia da COVID-19. A luxúria do sensacionalismo, que é viciosa pela sedução e exploração de vulnerabilidades ligadas ao medo da morte; a gula, por conteúdos de confirmação que disseminam inverdades no empenho de converter versões em fatos; a catequese do negacionismo gerando o ódio em ambientes epistêmicos restritivos; a ganância das novas tecnologias da economia da atenção pelo engajamento como nova commodity; a competição pelos holofotes da visibilidade midiática e ganhos derivados que incitam a soberba e a inveja dos pesquisadores que confundem o senso público com as fake researches - o que, em ciclo, nutrirão o sensacionalismo, gula, ódios e as ganâncias do capitalismo da atenção. Por fim, a preguiça é retratada como o vício capital dos que optam pela inação comunicativa. No conforto das bolhas renunciam ao diálogo por aversão ao dissenso, acomodando-se em posições de conforto epistêmico. Em síntese, o fenômeno das fake news na pandemia da COVID-19 é aqui retratado como a confluência de diversos vícios que se materializam como desinformação, na vacuidade comunicativa dos momentos nos quais somos obrigados a nos dirigir uns aos outros para partilhar nossas visões do mundo.

Las crisis sanitarias sacan a la luz "pecados" y deformidades morales de la sociedad que, aunque son evidentes cuando emergen, antes parecían latentes a la percepción colectiva. A través de la metáfora de los siete pecados capitales, el texto analiza el fenómeno de las fake news en las redes sociales y en el escenario de la pandemia del COVID-19. La lujuria del sensacionalismo que se ensaña con la seducción y la explotación de las vulnerabilidades ligadas al miedo a la muerte; la gula por los contenidos de confirmación que difunden las falsedades en el afán de convertir las versiones en hechos; el catecismo del negacionismo que genera el odio en entornos epistémicos restrictivos; la avaricia de las nuevas tecnologías de la economía de la atención por el compromiso como nueva commodity; la competencia por los focos de la visibilidad mediática y las ganancias derivadas que incitan a la soberbia, y la envidia de los investigadores que confunden el sentido público con falsas investigaciones -que, en ciclo, alimentarán el sensacionalismo, la gula, el odio y la avaricia del capitalismo de la atención. Por último, la pereza se presenta como el vicio capital de quienes optan por la inacción comunicativa. En la comodidad de sus burbujas renuncian al diálogo por aversión al disenso, instalándose en posiciones de comodidad epistémica. En resumen, el fenómeno de las fake news en la pandemia del COVID-19 se retrata aquí como la confluencia de varios vicios que se materializan como desinformación en la vacuidad comunicativa de momentos en los que nos vemos obligados a dirigirnos unos a otros para compartir nuestras visiones del mundo.

Seroprevalence and factors associated with SARS-CoV-2 infection among education workers after the first wave: the first cross-sectional study in Brazil.

BACKGROUND: The school community was heavily impacted by the Covid-19 pandemic, especially with the long time of school closures. This study aimed to analyze the seroprevalence of SARS-CoV-2 antibodies and possible factors associated with seropositivity for COVID-19 in teachers and other school staff, and to estimate the fraction of asymptomatic individuals by sex and age group. METHODS: We conducted a serological survey of SARS-CoV-2 infections. An analytical cross-sectional study was conducted in Fortaleza, Brazil. Teachers and other staff members from pre-schools to universities of higher education to were investigated. RESULTS: A total of 1,901 professionals participated in the study, of which 1,021 were staff and 880 were teachers. The seroprevalence of SARS-CoV-2 was 8.0% (152/1901). In the seropositive group, 48.3% were asymptomatic. There was a predominance of women (68.4%); and, 47.1% of the participants were between 31 and 45 years old. There was an increase in prevalence with increasing age. An inverse relationship was found for education level: more professionals with less education tested positive for COVID-19. The presence of an infected person living in the same household was significantly associated with positive results for COVID-19 among the professionals. CONCLUSIONS: This is the first study to report the seroprevalence of IgG against SARS-CoV-2 in Brazilian educational staff after the first wave of the disease. In this study, the seroprevalence was much lower than that in the general population. During school reopening, a small fraction of school workers showed serologically detectable signs of SARS-CoV-2 exposure.